Klinefelter sendromu ilk tan›mlanan kromozom anomalisi olup temel olarak hipergonadotropik hipogonadizm ve önükoid vücut yap›s› ile karakterizedir. S›kl› ¤›. ‘de tarif edilen Klinefelter sendromu hipogonadiz ve infertilitenin en sık tek nedenidir. Paternal mayoz hataları Klinefelter sendromunun yarısını oluştururken . Key words: Antisocial personality disorder, Klinefelter’s syndrome. ÖZET. Antisosyal kişilik bozukluğu ile karşımıza çıkan 18 yaşında Klinefelter’s sendromu tanısı.

Author: Yozshulkis Kajinos
Country: Greece
Language: English (Spanish)
Genre: Software
Published (Last): 8 June 2013
Pages: 61
PDF File Size: 4.41 Mb
ePub File Size: 4.56 Mb
ISBN: 607-7-54090-186-4
Downloads: 57516
Price: Free* [*Free Regsitration Required]
Uploader: Gujar

In patients with normal levels of testosterone, no replacement therapy is necessary. Privacy Policy We recommend you to read the terms of use below before you visit our website.

InJacobs and Strong stated that Klinefelter syndrome was a chromosomal disease and they were able to identify a 47,XXY chromosome structure created by an extra X chromosome causing this clinical picture 3. In patients with Klinefelter syndrome, azoospermia is detected with a very high percentage. Klinefelter syndrome and its variants: It may process the information or classify and save them on a database. Testicular examination should be performed in patients with infertility and if there is a clinical suspicion, a genetic analysis should be requested.

A natural person or a legal identity accessing to the ” SITE ” through online settings. Considerations for androgen therapy in children and adolescents with Klinefelter syndrome 47, XXY.

Klinefelter Sendromu

Turkish Law will be applied in practicing, interpreting the hereby “Terms of Use” and managing the emerging legal relationships within this “Terms of Use” in case of finding element of foreignness, except for the rules of Turkish conflict of laws.

The services provided and the context published within the ” SITE ” by third parties is not under the responsibility of “Turkiye Klinikleri”, institutions collaborated with “Turkiye Klinikleri”, “Turkiye Klinikleri” employee and directors, “Turkiye Klinikleri” authorized salespeople. Normal levels can be seen in patients with mosaic form, while much lower levels is seen in patients with high-chromosomal defects. Syndrome characterized by gynecomastia aspermatogenes without A-Leydigism and increased excretion of follicle stimulating hormone.

  EMU 0404 USB PDF

In Klinefelter syndrome, the most typical clinical manifestation is testicles not getting bigger despite the development of secondary sex characteristics. One of the most typical laboratory findings in patients is an increase in serum gonadotropin levels in puberty.

For this purpose, the sperm detected in testicular is isolated with the so-called testicular sperm extraction TESE method and then spermatozoa gets ejaculated into the ovum with the so-called intracytoplasmic sperm injection ICSI. During delivery, nothing specific could be observed in infants related with classic Klinefelter sndromu.

Isochromosome Xq in Klinefelter syndrome. Klinefelter syndrome and other sex chromosomal aneuploidies. IQ levels are usually normal in classic form but very sednromu levels can also be seen in patients with high malformations 10,15, As an alternative to injection, there are testosterone preparations orally or percutaneously administered.

Klinefelter Sendromu: klinefelter syndrome.

There is no spermatogenesis in patients with Klinefelter syndrome, thus the possibility of fertility is considered to be very low in general.

Chromosomal analysis from skin fibroblasts or testicular biopsy specimens may show mosaic chromosomal structure. Klinefelter syndrome in senddromu Extra X chromosome usually occurs during gametogenesis when ovum or sperm carries an extra X chromosome along with the normal sex chromosome.

Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions. Anyone accessing the ” SITE ” with or without a fee whether they are a natural kpinefelter or a legal identity is considered to agree these terms of use. Especially in the majority of patients with mosaicism, there are no symptoms to be found.


File:Klinefelter’s Syndrome XXY DNA.jpg

These changes will be published in the ” SITE ” periodically and they will be valid when they are published.

Gynecomastia patients might have high levels of estrogen, while no gynecomastia could be detected in patients with significantly higher estrogen serum levels. This is followed by cleft palate, inguinal hernia, cardiac abnormalities and radioulnar synostosis. Rates of chromosome abnormalities at different maternal ages.

File:Klinefelter’s Syndrome XXY – Wikimedia Commons

In patients with Klinefelter syndrome, serum testosterone levels usually begin to rise with puberty. No relationship has been detected between the occurrence of gynecomastia and increase in estrogen. An electronically signed contract between a natural or a legal identity benefiting from special services klinevelter Klinikleri” will provide and “Turkiye Klinikleri”.

In almost all patients with Klinefelter syndrome, an elevation of serum FSH is seen in lab findings 6,9, Bojesen A, Gravholt CH. Hypogonadism was found to be the most important cause of bone mineral deficiency. Prenatal and postnatal prevalence of Klinefelter syndrome: In recent years, however, fertilization can be achieved with some assisted reproductive methods in patients with Klinefelter syndrome.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

The most common malformation is clinodactyly. Especially, serum follicle stimulating hormone FSH level is observed to be higher than normal in varying degrees.