El Angiofibroma nasofaríngeo juvenil es un tumor benigno vascular (pero que tardíamente Se localiza en la pared posterolateral de la grita nasal a nivel del vínculo de la apófisis esfenoidal del hueso palatino. Esta localización conforma el. Nasal cavity, paranasal sinuses, nasopharynx – Nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally in the nasopharynx and nasal cavity, leading to manifestations such as nasal.

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Findings are similar to those described above. IIIa Erosion of the skull base with minimal intracranial extension.

Genetic evidence for an androgen-dependent tumor? Patients were aged years. It accounts for 0. Androgen receptor, juvenile angiofiborma, nasopharyngeal angiofibroma.

Imaging plays an important role in diagnosis, as biopsies should be avoided due to the risk of brisk hemorrhage, as well as staging.

Intracranial intradural tumor with infiltration of the juveni, sinus, pituitary fossa or optic chiasm. The main clinical presentation of JNA is unilateral nasal obstruction with or without epistaxis. These tests have led to the formulations of multiple classification methods, juvenip the FischRadkowskiAndrewsBremerand Antonelli methods 1,4,5,7,8.

It is, as the name suggests, very vascular and a biopsy can sometimes be fatal. Consistent expression of estrogen receptor beta. Although benign, it is a locally aggressive angiovibroma and invades the surrounding tissues and even bone through pressure resorption. By using this site, you agree to the Terms of Use and Privacy Angiofibromx. Arteriography followed by preoperative embolization and surgical resection is the treatment of choice.

From Wikipedia, the free encyclopedia. Analysis of these 13 patients suggests that fully endoscopic surgery is viable even in advanced cases of JNA. This page was last edited on 29 Septemberat This was a retrospective cohort study.


The nasap is limited to the sphenopalatine foramen, nasopharynx, and nasal cavity without bone destruction. MRI is used posttreatment to detect residual or recurrent tumor mass and to monitor the effects of radiotherapy. These techniques help to establish the exact site, extension and relation of the tumor to the adjacent structures such as blood vessels and nerves.

Strayer; Emanuel Rubin Long-term tumor recurrence has been reported due to incomplete initial resection.

Juvenile nasopharyngeal angiofibroma

Case 5 Case 5. Endoscopic surgery in treatment of juvenile nasopharyngeal angiofibroma.

This study was approved by the local research ethics committee under protocol No. None of the patients who underwent fully endoscopic surgery developed any immediate or delayed complications. Antral sign or Holman-Miller sign forward bowing of posterior wall of maxilla is pathognomic of angiofibroma.

Other search option s Alphabetical list. Invasion of the intracranial region may lead to cranial nerve palsy. Molecular pathogenesis of juvenile nasopharyngeal angiofibroma in Brazilian patients.

Juvenile nasopharyngeal angiofibroma | Radiology Reference Article |

Douglas R, Wormald PJ. Recent immunohistochemical and genetic studies throw some light on abgiofibroma topic. Juvenile nasopharyngeal angiofibromas are benign but highly vascular tumours. The development of minimally invasive techniques has led to the increased use of endoscopic surgery for the treatment of nasopharyngeal angiofibroma 21making it ideal for tumors confined to the nasopharynx, nasal cavity, and sphenoid sinus with minimal extension into the pterygopalatine fossa 10,12,13,15,18, The most significant juvenip is blindness, for patients with occlusion of the ophthalmic or middle cerebral artery through the collateral circulation.

Bone destruction negligible or limited to the sphenopalatine foramen. Some authors maintain that endoscopic approaches should only be used when the tumor is confined to the nasal cavity, paranasal sinuses, pterygopalatine fossa, or infratemporal fossa. Articles Cases Courses Quiz. Medical treatment and radiation therapy are only of historical interest. According to the adopted categorization scheme, these patients would correspond to grade IIIb of the Andrews classification.


A higher density toward the periphery is noted, which was seen in the present case too. Removal is important in preventing nasal obstruction and recurrent epistaxis. Nasopharyngeal angiofibroma is a histologically and biologically benign tumor with aggressive behavior due to its location and associated symptoms including significant epistaxis and nasal obstruction Conflicts of interest There are no conflicts of interest.

Epistaxis, rhinorrhea and pain may also be seen. Nasopharyngeal angiofibroma[TI] free full text[sb].

This was a retrospective cohort study of all patients with JNA with intracranial extension Radkowski grade IIIa treated with endoscopic, endoscopic-assisted, and external surgery from January of to May of Efforts naeal determine the pathogenesis of the tumor have been done by studying the expression of various growth factors and oncogenes such as C-KIT and C-MYC.

Moreover, the mean blood loss in these patients was mL. J Oral Maxillofac Pathol. Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Kuvenil carcinoma.